The spread of a supratentorial glioma to the cerebellopontine angle is infrequent. Its management is not yet established, and its prognosis is unfavorable.Methods: a clinical case documented with images (preoperative, operative, and postoperative) and a review of the literature are presented.
A Few cases of an extremely rare Glioblastoma (GB) with epithelial (glandular) and atypical metaplasia known as adenoid variant have been reported worldwide. Epithelial metaplasia can occur in gliosarcoma or glioblastoma which can lead us to think of metastatic carcinoma as a differential diagnosis. They usually react to Glial fibrillary acidic protein (GFAP) and low molecular weight cytokeratin (CK7). This tumor is considered extremely rare but it is not recognized as a different entity by the World Health Organization. Adenoid differentiation can be due to primitive neuroepithelial cells, mechanical compression, or the histological response to the tumor. Metaplasia in tumors not originated in the nervous system is not uncommon. Gliosarcomas are genetically similar to primary GB: 20% to 40% of tumors harbor TP53 mutations, PTEN deletions, and CDKN2A1 deletions.
Large sphenoid wing meningiomas are difficult to resect completely as they tend to cause neuropathies, visual disturbances, and encasement of the main arteries. The target of surgical management is a gross total resection while sparing nearby nerves and arteries. To date, only a few cases using endovascular procedures for vascular control during tumor surgery had been published in the literature.
Cancer pain can often be considered intractable, thus using non-conservative techniques such as Moricca's Pituitary Neuroadenolysis (MPNAL). This technique is shown to be viable in suppressing pain transmission, being seen as an alternative for cancer patients.
Angiocentric gliomas are rare superficial slow growing brain tumors with few reported cases. They usually affect children and young adults . They were first recognised as a distinct clinicopathological entity in 2007 and classified as WHO grade I tumors. Seizures are the classical presentation with over than 95% of patients presenting with intractable seizures. The origin of this tumor is controversial. The treatment is surgical and the outcome is favorable.
Meningiomas with extracranial metastases are seldom. They represent 1% of all meningiomas. Lungs are the most common site of these metastases. To the best of our knowledge, only twenty cases of such association have been reported in the litterature in the last twenty years.
Low-grade gliomas are slow-growing infiltrative tumors that progress as tumors of the same grade or higher grade. These tumors will be the cause of death for most patients. Early extended resection is the current standard of care. Thus, we intend to identify and understand the influence of clinical and therapeutic factors on overall survival and progression-free survival.
Neuroendocrine tumors are challenging malignant lesions due to their usually late diagnosis and limited treatment options. To the authors knowledge, there are no reports in literature to date that demonstrate subdural occupation due to this type of tumor.
Intracranial schwannomas represent 5-10% of intracranial tumors, however, craniocervical junction localization of these lesion is uncommon being up to 5%. The localization of these tumors offer a challenge to the neurosurgeon in terms of choice of approach and complete resection.
Solitary Craniocerebral Plasmacytoma is the least common form of extramedullary solitary Plasmacytoma. Cerebral solitary Plasmacytoma is very rare. The world literature counts only 7 intracranial cases. CASE REPORT - The authors report a case of cerebral tumour of solitary Plasmacytoma in a 52 years female who presented to hospital with headache and difficulty in walking for 6 months.
Multiple sclerosis is a chronic demyelinating disease of the central nervous system. Tumor-like manifestation of multiple sclerosis is one of the rare clinical variants and is frequently source of misdiagnosis.Case presentation :We report the case of a 45-year-old man with no medical background, who presented bilateral visual deficits more prononced in the left eye who have spontaneoustly regressed after two months . Two months later the patient consulted with right leg motor deficit, sensitive deficit, headache and bilateral papilledema.
Cerebellar liponeurocytoma is a rare tumor of the posterior fossa that has many morphological similarities to medulloblastoma and neurocytoma. It typically involves the cerebellar hemispheres of middle-aged to older adults. We report a rare case of a cerebellar liponeurocytoma.
Malignant myopericytoma (MMPCT) is an exceedingly rare soft tissue tumour with only 14 documented cases in the English literature. Myopericytomas can occur in association with HIV-AIDS and have a predilection for internal organs such as the bronchus, larynx, liver and brain. These tumours can be associated with Ebstein-Barr virus (EBV). Out of these 14 cases, three had a positive Ebstein-Barr virus encoded small RNAs (EBER). In this case report we present the second ever documented case of a malignant myopericytoma with a positive EBER found intracranially.
Meningiomas are usually tough, fibrous and very vascular tumours. Ultrasonic aspirators are well known for use during meningioma surgery. However, surgeons experience great difficulty with the tougher and more vascular tumours making them not amenable to an ultrasonic aspirator. Laser technology can also be implemented, but with its own set of advantages and disadvantages. In this case series we present four patients who had confirmed meningiomas on histology. Their tumours were removed with radiofrequency ablation plasma technology (RFA). This allowed easy removal of the tumours and maintenance of haemostasis simultaneously. RFA plasma technology has coagulation and debulking functions available on the same instrument, which leads to a quicker surgery with less blood loss. These cases are the first reported use of RFA plasma technology for the purpose of meningioma removal in South Africa.
Brain metastases (BMs) result in a neurological deficit, seizures, paralysis, and cognitive decline, increasing human and financial costs. In patients with cancer, the proportion of patients suffering from BMs ranges from 9 to 50%. However, the number of studies that evaluate prognostic factors in patients with BMs surgical treatment among the Hispanic population in Latin-American countries is scarce.
Open surgery is the historical standard treatment of skull base neoplasms, being a well-characterized procedure dating back several decades. However, over the past 20 years, endoscopic technology has revolutionized skull base surgical approaches, increasing interest and achieving resection rates comparable to those obtained using conventional approaches.
Medulloblastoma is the most common malignant pediatric brain tumor and a leading cause of cancer-related death, accounting for 10-20% of brain tumors in children, but are observed infrequently in adults, accounting for an estimated 1% of primary central nervous system tumors in adults. This video presentation reports two rare cases of medulloblastoma in pregnant patients and a review of the literature.
Glioblastoma (WHO grade IV astrocytoma) is the most common and invective primary brain tumour in adults. It is addressing an exceptionally heterogeneous gathering of neoplasms that are among the most forceful and challenging malignancies to treat.